The question here is, if cathodal tDCS of the contralesional (unaffected) hemisphere is able to improve motor function of the paretic hand, can this protocol also improve motor learning in these patients?
This article clearly highlights the potential of tDCS for restoring plasticity in the motor cortex after stroke and sheds new light on how it might do so.
This will appear at www.f1000.com
1. Reis, J. et al. Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation. Proceedings of the National Academy of Sciences of the United States of America 106, 1590–5 (2009).
2. Hummel, F. C. et al. Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke. Brain 128, 490–9 (2005).
3. Fregni, F. et al. Transcranial direct current stimulation of the unaffected hemisphere in stroke patients. Neuroreport 16, 1551–5 (2005).
4. Stagg, C. J. et al. Cortical activation changes underlying stimulation-induced behavioural gains in chronic stroke. Brain : a journal of neurology 135, 276–84 (2012).
5. Grefkes, C. & Fink, G. R. Reorganization of cerebral networks after stroke: new insights from neuroimaging with connectivity approaches. Brain 1264–1276 (2011).doi:10.1093/brain/awr033
6. Zimerman, M. et al. Modulation of Training by Single-Session Transcranial Direct Current Stimulation to the Intact Motor Cortex Enhances Motor Skill Acquisition of the Paretic Hand. Stroke; a journal of cerebral circulation 2185–2191 (2012).doi:10.1161/STROKEAHA.111.645382